بررسی کارایی پلیمر قالب مولکولی در حذف بقایای آنتی بیوتیک اکسی تتراسایکلین در نمونه‌های سینتتیک و شیر

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانش‌آموخته کارشناسی ارشد مهندسی پلیمر، باشگاه پژوهشگران جوان و نخبگان، واحد یزد، دانشگاه آزاد اسلامی، یزد، ایران

2 دانشجو دکتری نساجی، باشگاه پژوهشگران جوان و نخبگان، واحد یزد، دانشگاه آزاد اسلامی، یزد، ایران

3 دانشجوی کارشناسی ارشد مهندسی صنایع غذایی، دانشکده کشاورزی و منابع طبیعی، واحد یزد، دانشگاه آزاد اسلامی، یزد، ایران

4 دانشیار، دانشکده مهندسی نساجی و پلیمر، واحد یزد، دانشگاه آزاد اسلامی، یزد، ایران

چکیده

از نگرانی‌های رو به رشد چند دهه اخیر در زمینه آلودگی محیط‌زیست، ایجاد مقاومت دارویی در انسان به‌علت مصرف آنتی‌بیوتیک‌ها می‌باشد. هدف از انجام این پژوهش سنتز ذرات پلیمر قالب مولکولی جهت حذف آنتی‌بیوتیک اکسی‌تتراسایکلین از نمونه‌های آبی و بیولوژیکی (نمونه شیر) به روش غیرکووالانسی می‌باشد. تأثیر عوامل محیطی نظیر pH محلول (10-2)، زمان تماس (120-5 دقیقه) و مقدار ذرات پلیمر قالب مولکولی (1- 1/0گرم بر لیتر) در بهینه‌سازی شرایط حذف مورد بررسی قرار گرفت. ذرات پلیمری سنتز شده با استفاده از میکروسکوپ الکترونی روبشی و جذب و واجذب گاز نیتروژن شناسایی شدند. نتایج نشان داد که راندمان حذف در شرایط خنثی حداکثر بوده و با افزایش مقدار ذرات پلیمری راندمان حذف نیز افزایش می‌یابد. بهترین شرایط حذف اکسی‌تتراسایکلین در 5/6= pH، زمان 90 دقیقه و حداکثر ظرفیت جذب 280 میلی‌گرم برگرم تعیین شد. کارایی پلیمر سنتز شده در حذف اکسی‌تتراسایکلین از نمونه شیر مورد ارزیابی قرار گرفت. عملکرد ذرات پلیمری در حذف آنتی‌بیوتیک در نمونه‌های شیر تهیه شده از دامداری نشان داد که این نوع جاذب‌ها می‌توانند به کاهش مؤثر بقایای آلودگی‌های دارویی در نمونه‌های لبنی کمک کنند.

کلیدواژه‌ها


عنوان مقاله [English]

Evaluation of Molecularly Imprinted Polymer Performance for Removal of Oxytetracycline from Aqueous and milk

نویسندگان [English]

  • S. Jafari 1
  • Mohammad Dehghani 2
  • Elham Ghorashi 3
  • Navid Nasirizadeh 4
1 M. Sc. Graduate of Polymer. Young Researcher and Elite Club, Yazd Branch, Islamic Azad University, Yazd, Iran
2 Ph.D. student on Textile, Young Researcher and Elite Club, Yazd Branch, Islamic Azad University, Yazd, Iran
3 Graduate of Food Science and Technology, Department of Agriculture and Natural Resources, Yazd Branch, Islamic Azad University, Yazd, Iran
4 Associate Professor, Department of Textile and Polymer Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran
چکیده [English]

Among the growing concerns over recent decades in the field of environmental pollution, is the use of antibiotics increase bacterial resistance to antibiotics used in human body. The aim of this research was to synthesis of Molecularly Imprinted Polymer (MIP) particles for the Oxytetracycline (OTC) antibiotic removal from the aqueous and milk. The influence of different parameters such as pH (2-10), contact time (5-120 min) and MIP amounts (0.1 – 1.0 g/L) was studied on optimization of OTC removal. The synthesized MIP particles was characterized by scanning electron microscopy and absorption and desorption of nitrogen (BET). The results showed that the removal efficiency is higher in neutral pH and with increasing amounts of MIP particle, removal efficiency increases. The best condition for OTC removal was determined at pH, 6.5, 90 min and 280 mg/g as maximum absorption capacity. The MIP performance for OTC removal from milk was investigated too. The performance of MIP polymer particles in OTC removal in milk samples supplied from an animal husbandry in Yazd showed that these adsorbents can help to effectively reduce the residues of drug contaminants in dairy samples.

کلیدواژه‌ها [English]

  • Molecularly Imprinted Polymer
  • Removal
  • Oxytetracycline
  • Milk
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